Conference Schedule

Day1: March 26, 2018

Keynote Forum

Biography

Dietmar Schranz, MD was a Resident and Fellow in Pediatrics, Neonatology, Pediatric Intensive Care & Cardiology with follow-up position as Assistant Professor (PhD) in Pediatric Cardiology and Intensive Care at the Gutenberg University Clinic Mainz, Germany. During 1996-2017 he was a University Professor (C4), Justus-Liebig University Giessen, Germany, Chair of the Department of Pediatric Cardiology, Pediatric Heart Center, JLU-Giessen (Germany). Since 2017 he is a Consultant in University Clinic Frankfurt & Wuxi, China. He has publications of more than 200 peer-reviewed papers in reputed journals and more than 100 invited talks world-wide. He has membership in multiple German & European societies and he is a Reviewer of Lancet, Circulation and many other high-ranked Journals.
 

Abstract

Heart failure (HF) in children is a serious public health concern. HF has numerous etiologies, but unspecific symptoms. There is interplay among neurohumoral, and molecular abnormalities. Major advances in chronic heart failure (cHF) therapy have been achieved in adult patients, while research regarding the mechanisms and therapy of chronic heart failure in children has lagged behind. However in any case, the current chronic therapy of systolic HF focused on loop-diuretics, fluid restriction and digoxin as well as the definition of end-stage HF is inacceptable; not at least in context of the potentials of regeneration reciprocal to the patient’s age. Therefore, therapy has to extend to selective ß1-blocker, tissue ACE-I and mineralocorticoid blockers, and loop-diuretics avoided as ever possible. The efficacy of endogenous neurohumoral inhibition can easily monitored, even by parents only looking at surrogate parameters as heart and breath rate as well as systolic and diastolic blood pressure. Echocardiographic control of cardiac function has to include synchrony and parameters of ventriculo-ventricular interaction (VVI). Optimizing the left ventricular preload is advocated as an 
important part of a regenerative strategy. Interventional aspects of such a regenerative favored HF therapy include creation of a restrictive interatrial communication, placing a reversible pulmonary artery banding and stem cells replacement.
 

Biography

Michael J Cooper graduated from Tel-Aviv University Medical School in 1977. He is specialized in Pediatrics followed by a Pediatric Cardiology Fellowship at University of California San Francisco (UCSF) Medical Center, USA. He remained at UCSF after fellowship and became full Professor of Pediatric Cardiology in 1988. Additionally, he conducts cardiovascular screening for young athletes at Northern California high schools. He also volunteers biannually in Palestine for children who lack access to care. In his free time, he publishes novels of historical fiction.

Abstract

The sudden cardiac death (SCD) of a young athlete is a rare but catastrophic event that sends shock waves through a community, and when this tragedy involves a high profile athlete being viewed by tens of thousands of spectators and millions more by television, the shock waves spread around the world. Though only about one out of 200,000 young athletes have an underlying heart defect that can lead to SCD, the farreaching impact of the event predictably generates a great deal of discussion among the general public and within the medical community. Pre-participation screening offers the important possibility of primary prevention of SCD since the outcome of lethal cardiovascular disorders is usually irreversible. We will explore the cardiovascular aspects of pre-participation screening beginning with a discussion of the incidence and nature of the cardiovascular anomalies that cause SCD in the young. These include hypertrophic cardiomyopathy, arrhythmogenic right ventricular dysplasia, aortic dissection due to Marfan syndrome, congenital and acquired coronary artery anomalies, and electrophysiological anomalies including WolffParkinson White syndrome (WPW), Long QT, Brugada, and CPVT (catecholaminergic polymorphic ventricular tachycardia). We will focus on how these potential causes of SCD might best be detected. Recognizing variations in epidemiology and etiology of SCD in North America, Europe and Asia, we will discuss the varying application of screening modalities, which include the use of the questionnaire, physical examination, electrocardiography (EKG) and exercise EKG. In this context, we will review the scope and nature of community-wide screening in USA as it compares with other countries, and we will revisit the controversy regarding the exclusion of EKGs from the AHA guidelines. The audience will be able to use what they learn by reviewing the incidence of 
various causes of sudden cardiac death (SCD) in young athletes and we will heighten awareness of these entities. Empowered with the knowledge regarding the etiologies that may lead to SCD in young athletes, the audience will be vigilant about these entities and know when to refer for specialty evaluation and care. Knowing the power of the EKG in expanding detection for many etiologies that may lead to SCD in young athletes, the audience will appreciate and obtain this information. This will help the audience in their job by empowering them with the knowledge regarding the etiologies that may lead to SCD in young athletes and the audience will be vigilant about these entities and know when to restrict athletes pending specialty evaluation. The other benefits include a discussion of etiologies that may lead to SCD in young athletes will have immediate impact on the clinical practice of pediatricians in the context of the pre-participation sports physical. This will heighten the awareness of clinically important details enhancing the detection of potentially lethal cardiovascular anomalies. This discussion will also provide the substrate for population research and registries to monitor the impact of enhanced detection.
 

Biography

Aris Lacis, MD, PhD is a Cardiac Surgeon and Professor who graduated from Riga Medical Institute in 1961. He was a General and Thoracic Surgeon in P Stradina University Hospital in Riga (1964–1969); Thoracic and Cardiac Surgeon in the Latvian Centre for Cardiovascular Surgery (1969–1994). From 1994 to 2012 he was the Head of Pediatric Cardiology and Cardiac Surgery Clinic in University Children’s Hospital, Riga; since 2012 he is a Consulting Professor of this Clinic. He is the President of Latvian Association for Pediatric Cardiologists and Author of 395 scientific publications, 3 monographs and 13 patents. He is an Investigator in more than 10 clinical trials including cardiosurgical procedures performed under deep hypothermia, hybrid procedures etc. In May 2009 he became first in the world to use transcutan intramyocardial delivery autologous bone marrow derived progenitor stem cells for 3 months old patient suffering from idiopathic dilated cardiomyopathy.
 

Abstract

Statement of the problem: Dilated cardiomyopathy is a serious problem in pediatric cardiology praxis. Despite the relatively low incidence of 0.57 to 2.6 per 100000 children the mortality rate is high. One third of patients die within the first year after diagnosis. Up to 40% of these patients are defined as idiopathic dilated cardiomyopathy (IDCM), characterized by ventricular dilatation and systolic dysfunction. Researchers have reposted that conventional medical therapy does not improve the outcome of the disease; however recent clinical studies have suggested bone marrow derived autologous mononuclear cells as a promising therapy option. Pulmonary arterial hypertension (PAH) is characterized by increased pulmonary vascular resistance resulting in extensive heart structural changes leading to right heart failure and death. PAH is characterized by obstruction of small pulmonary arteries leading progressive increase in vascular resistance. Locally implanted stem cells may trigger the neovascularization process in the lung potentially leading to a decrease of pulmonary artery pressure. Methodology: For treatment of IDCM we prefer to use transcutan intramyocardial administration of autologous bone marrow derived mononuclear stem cells, combined with ultrasound monitoring. In patients with PAH intrapulmonary transplantation of stem cells was performed using: intravasal injection of the stem cells by catheterization pulmonary arteries and directly in the lung tissues by using standard thoracentesis technique, performed under chest radiological control. Conclusions: Ten years’ experience applied wisely, the stem cell therapy appears to be a safe and effective way for stabilization 
of critically ill patients with both severe pulmonary arterial hypertension and idiopathic dilated cardiomyopathy. This method provides additional opportunities for symptomatic treatment and serves as a bridge for potential heart and lung transplantation 

Tracks

  • Pediatrics | Pediatric Cardiology | Pediatric Urology | Pediatric Nephrology
Location: Macallan
Speaker

Dietmar Schranz

Johann-Wolfgang Goethe University, Germany

Chair

Speaker

Micheal J Cooper

UCSF-Benioff Childrens Hospital, USA

Co Chair

Biography

Hanna Alobaidy has completed her MB BCh from Faculty of Medicine, Alexandria University, Egypt in 1980 and Postdoctoral studies in Pediatrics from Karolinska Institute Stockholm Sweden, 1990. She is a Consultant of clinical pediatrics and inborn errors of metabolism. She is currently serving as Consultant Metabolist in outpatient clinic Alkhadra Hospital, Tripoli, Libya. She has committed to a career in Academic Medicine and has over 20 years of experience of undergraduate and postgraduate medical education in University of Tripoli Medical College. She has published papers in national and international peer-reviewed medical journals with over 25 citations. Her top clinical researches are: The 1st study and reference report about the “Pattern of metabolic disorders in Libya, long term experience in tyrosinemia type I with NTBC (17years) and Niemann-Pick C disease follow up”.

Abstract

Biography

Rose Mary S Stocks is the Residency Program Director for Otolaryngology, Head & Neck Surgery Department at UTHSC. She is a fellowship trained Pediatric Otolaryngologist with a Doctorate in Pharmacy and a long bench research history. She has conducted numerous NIH-funded research endeavors with an emphasis on ototoxicity and its prevention in the administration of chemotherapy in the guinea pig model. She has participated in, and published her experience in extra-uterine, prenatal surgical repair of defects of the head and neck (the EXIT procedure). She has served as Research Mentor to numerous residents over the years and greatly increased the amount of scholarly activity within the department. She has taught courses at a national level for the American Academy of Otolaryngology, Head and Neck Surgery on Down’s Syndrome for the Otolaryngologist and Management of the Difficult Pediatric Airway. She teaches first year medical students about examination of the ear, nose, and throat and is a tireless surgical educator in the training program. She is a Member of the LeBonheur Multidisciplinary Cleft Lip and Palate Team and devotes her expertise to the care of these patients and their families.

Abstract

Biography

Singh D S is an Associate Professor of Pediatric Department in Kathmandu University Hospital, Dhulikhel, Kavre, Nepal. She has done her Postgraduation in Pediatric Nutrition (Boston University). She has studied her Medicine (MBBS) in University of Science and Technology, Chittagong, Bangladesh. She is MD (Pediatrics), Kathmandhu University, Dhulikhel, Kavre, Nepal. Her research works include: Risk factor of low birth weight babies born in Dhulikhel Hospital; Incidence, risk factor and outcome of birth asphyxia cases born in Dhulikhel Hospital; Outcome of meconium stain liquor babies born in Dhulikhel Hospital; Incidence, clinical profile and antibiotic sensitivity in urinary tract infection in Dhulikhel Hospital; Incidence, clinical profile and antibiotic sensitivity in enteric fever in Dhulikhel Hospital; and clinical profile, radiological resolution and risk factor associated with fatal pneumonia. She has attended conferences on Pediatric Epilepsy in Nationwide Children’s Hospital, Columbus, USA; Subspecialty conference of Pediatric organized by Nepal Pediatric Society, workshop on curriculum review on Pediatric Nutrition organized by Child Health Division of Government of Health, curriculum review of MBBS; workshop on Database Management of newborn child. She has done paper presentations in Nepal Pediatric Society Conference on the following topics: Incidence, clinical profile and antibiotic sensitivity in urinary tract infection in Dhulikhel Hospital; Incidence, clinical profile and antibiotic sensitivity in enteric fever in Dhulikhel Hospital; and clinical profile, radiological resolution and risk factor associated with fatal pneumonia. 

Abstract

Biography

Banafshe Dormanesh has completed her Medicine in 1993; Pediatric Specialty in 1997 and Pediatric Nephrology subspecialty in 2002 from the Tehran University of Medical Sciences. She is an Associate Professor in Pediatric Nephrology and is the Head of Pediatric Department in Faculty of Medicine. She has published more than 60 papers and book chapters. She is an Associate Editor in AMHSR Journal and Head of the Editorial Board Member (Clinical Sciences and Practice, Family Medicine) in JAMM Journal. 

Abstract

Biography

Maria NeamÈ›u, is the Head of Paediatrics Department of the Municipal Hospital, BalÅ£i, Republic of Moldova. She is a specialist in Paediatric Cardiology with more than 34 years of experience in the field. Her experience and passion for medical activity is implemented through different activities as: depth knowledge in providing emergency medical care to patients with cardiac pathologies, administration of the children’s hospital with a capacity of 135 beds, teaching at the medical college, which is the key moment to provide qualitative emergency assistance to children. Her professional knowledge and skills are also reconfirmed by attending and publishing scientific papers at the cardiology congresses in London, Tel-Aviv, Brussels, Bucharest and Barcelona. 

Abstract

Day2: March 27, 2018

Keynote Forum

Biography

Rose Mary S Stocks is the Residency Program Director for Otolaryngology, Head & Neck Surgery Department at UTHSC. She is a fellowship trained Pediatric Otolaryngologist with a Doctorate in Pharmacy and a long bench research history. She has conducted numerous NIH-funded research endeavors with an emphasis on ototoxicity and its prevention in the administration of chemotherapy in the guinea pig model. She has participated in, and published her experience in extra-uterine, prenatal surgical repair of defects of the head and neck (the EXIT procedure). She has served as Research Mentor to numerous residents over the years and greatly increased the amount of scholarly activity within the department. She has taught courses at a national level for the American Academy of Otolaryngology, Head and Neck Surgery on Down’s Syndrome for the Otolaryngologist and Management of the Difficult Pediatric Airway. She teaches first year medical students about examination of the ear, nose, and throat and is a tireless surgical educator in the training program. She is a Member of the LeBonheur Multidisciplinary Cleft Lip and Palate Team and devotes her expertise to the care of these patients and their families.
 

Abstract

Objective: 
"Initial management of infants with a cleft lip and palate " is directed to the primary care physician who are the first to care for these infants. The feeding, hearing loss, airway issues, psychological support as well as their role for preparing this infant their first operation. The cleft deformity and the timing of the various surgeries.

 

Biography

Stuparu Cretu Mariana is a Pediatrician and Generalist, also specialist in general and pediatric ultrasound, family planning and health management. She has completed her PhD in Pediatrics at 2013 from Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. Now, she is the Medical Director of Obstetrics Ginecologie Hospital BunaVestire of Galati and Associate Professor at Faculty of Medicine and Pharmacy, Dunarea de Jos University of Galati. She is concerned about different areas of health, preferential nutritional health of the population, metabolic syndrome, adolescent health, pediatric gynecology, health education. She has presented several research papers at different conferences and congresses.
 

Abstract

Clinical studies have demonstrated that inulin-type fructans added to infant food formula have significant effects on intestinal flora because of their prebiotic potential and influence the innate and adaptive immune response favorably. Therefore, people who have consumed inulin have a steady state of wellbeing. Our main goal was to extract, isolate and characterize the inulin-type fructans from Cichorium intybus and Taraxacum officinale roots in order to evaluate the prebiotic activity of this polysaccharide. The sources of inulin, Cichorium intybus (chicory) and Taraxacum officinale (dandelion) roots, was collected from Romanian south-east spontaneous flora. The inulin was extracted from plant material by fractionation with different solvents. The content of saccharides from the organic extracts was quantified using spectrophotometric methods and HPTLC technique and commercial inulin, as standard solution. The presence of other different chemical compounds from extracts was highlighted using attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR). The prebiotic activity of inulin from extracts was performed in the presence of Lactobacillus plantarum strains and a commercial product. The highest content of inulin-type fructans was found in Cichorium intybus roots compared to the Taraxacum officinale roots extract. Both plant extracts showed similar functional groups like the inulin standard solution (C-C: 1018÷1044 cm-1 and C-OH: 1106.06÷1114 cm-1). Thus, the chemical structure of 
the compounds found in the plant extracts is almost similar to that of the standard solution of inulin. Lactobacillus plantarum strains showed a significant growth dynamics in the presence of both extracts compared to the sample represented by a commercial product. In conclusion, Taraxacum officinale roots are characterized by an essential prebiotic potential due, like of Cichorium intybus, to their significant inulin content and can be used as natural additives resources to improve the textural and organoleptic properties of various food daily products for children.
 

Tracks

  • General Pediatrics | Neonatology and Perinatology | Pediatric Genetics | Pediatric Nephrology and Urology
Location: Macallan
Speaker

Rose Mary S Stocks

University of Tennessee Health Science Center, USA

Chair

Speaker

Mariana Stuparu Cretu

University Dunarea de Jos of Galati

Co Chair

Biography

Iram Naz has completed her MBBS in 2014 from Xi’an Jiaotong University, China and now is a Master’s (Pediatrics) student in Xi’an Jiaotong University.

Abstract

Biography

Maryam Moradian has completed her Residency in pediatrics, Tehran University of Medical Sciences (Children’s Medical Center) and Mashhad University of Medical Sciences. She was the Director of pediatrics echocardiography lab, Rajaie Cardiovascular Medical and Research Center from 2011-2013. She has published more than 14 papers in reputed journals. 

Abstract

Biography

Kyrina Anastasia has completed her Medical studies from National and Kapodistrian Athens University. She has worked as a Pediatric Trainee at General Hospital of Kozani in Greece. She has done her neonatal rotation at Chelsea and Westminster Hospital in London. She is now a Clinical Fellow in Pediatrics and Neonates at Countess of Chester Hospital in Liverpool.

Abstract

Biography

Hanna Alobaidy has completed her MB BCh from Faculty of Medicine, Alexandria University, Egypt in 1980 and Postdoctoral studies in Pediatrics from Karolinska Institute Stockholm Sweden, 1990. She is a Consultant of clinical pediatrics and inborn errors of metabolism. She is currently serving as Consultant Metabolist in outpatient clinic Alkhadra Hospital, Tripoli, Libya. She has committed to a career in Academic Medicine and has over 20 years of experience of undergraduate and postgraduate medical education in University of Tripoli Medical College. She has published papers in national and international peer-reviewed medical journals with over 25 citations. Her top clinical researches are: The 1st study and reference report about the “Pattern of metabolic disorders in Libya, long term experience in tyrosinemia type I with NTBC (17years) and Niemann-Pick C disease follow up”. 

Abstract

Biography

Ruba Abo Essa has completed her MBBS from King Khalid University 2011. She has Saudi board in pediatrics from Saudi commission for health specialties, Saudi Arabia, Nov 2015 and Arab board in pediatrics from Arab board of health specializations, May 2016. She is currently a pediatric senior registrar and the director of pediatric residency training program, Abha maternity and children’s hospital. She has published many papers in reputed journals 

Abstract

Biography

Katrien Francois is a Congenital Cardiac Surgeon at the University Hospital Ghent, Belgium, and currently the Head of the Cardiac Surgery Department at the same hospital. She received her surgical training at the University Hospital Ghent, and congenital cardiac surgery training at Great Ormond Street Hospital for Sick Children, London. She obtained her PhD with a thesis on “Surgical palliation of the functionally univentricular heart”. She has published more than 100 papers in peer-reviewed journals. 

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